Tuesday, January 5, 2016

Genetics



Genetics.....



Mendelian Genetics 6.3 - 6.5

The groundwork of our understanding of genetics came from the Austrian monk known as Gregor Mendel in the mid 1800's.

He was fascinated with pea plants and used them in his experiments because they reproduced quickly.

He crossed two different color pea plants which he thought were "purebred" and observed their offspring traits (characteristics passed from parent to offspring).




He concluded that there was something causing the pea plant to appear different than the others.

This same concept can be used for our genetic makeup....

We have different forms of genes in our chromosomes called Alleles represented by letters. 



The terms Dominant (Strong allele) and Recessive (Weak allele) are used to determine the outcome of certain traits.

Dominant: Expressed when at least one strong allele is present and is most commonly seen in a population.

Recessive: Only expressed when two identical weak alleles are present.


Homozygous vs Heterozygous




Using this information we are able to determine the Genotype (Genetic makeup=GG, gg, or Gg) and the Phenotype (Physical characteristic=brown, tall, round etc....)



Tutorial on Punnett Squares 

Monohybrid Cross: When one trait is used for example one letter T (TT x tt) or(Tt x tt) or (tt x tt). The capital letter is written first.



Practice
More Practice

Dihybrid Cross

Laws of Genetics:

Law of Independent Assortment - alleles separate independently from each other during meiosis. 

What does this mean? 

This means one trait can result independently of another trait.

Tall is dominant to short plant. Green pea color is dominant to yellow.

Can the plant come out Short with Green peas? or Tall with yellow?

Dihybrid Cross: When two traits are used for example two letters R and Y. 
Male RrYy x Female RrYy (Tall & Green).

Possible Combos: 
Male:
Female:



Lets try some Punnett Square Problems....

Brown eyes (B) are dominant to blue eyes (b). Tall height (G) is dominant to short (g).

What are the chances of a child being born with blue eyes and tall in height.


Hunger Games
Practice 1
Practice 2
Dihybrid Cross Practice



Practice

Tall Height is dominant = T
Short Height is recessive = t
Purple Flowers are dominant = F
White Flowers are recessive = f
Straight Hair is dominant = H
Curly Hair is recessive = h


MONOHYBRID CROSS

Ex1: Tt x TT



Ex2: FF x ff



Ex3: Heterozygous parent for purple flowers is crossed with homozygous recessive for white flowers.



Ex4: Two heterzygous parent for tall height is crossed.


DIHYBRID CROSS

Ex5: TTHh x Tthh








Ex6: A tall and purple homozygous dominant plant is crossed with a heterozygous plant.








PEDIGREE ANALYSIS



Case of the Tell Tale Gene




Monday, November 30, 2015

Monday, November 9, 2015

Chapter 8

Chapter 8 DNA and Protein Synthesis

Due 11/16
300 word essay (typed or written) explaining if you agree or disagree with  Watson and Crick receiving the Noble Peace Prize.
View, take notes, & Answer the questions
Secret of Photo 51



Section 8.1
Griffith Experiment



Hershey-Chase Experiment




Section 8.2


DNA is made up of 3 structures (phosphate, 5 carbon sugar, nitrogenous base)


Watson and Crick Model

Base Pairing Rules
Each base held to the other by Hydrogen Bonds




Section 3: DNA Replication






Question on STAAR






DNA REPLICATION

Section 4 & 5 
Transcription (in the nucleus using DNA template)

19 9 *  22 15 21 19 *  20 18 1 4 21 9 19 5 26 *  3 5 12 1  * 
1 12 15 18 19 *  22 15 21 19 *  15 2 20 9 5 14 4 18 5 26 *  
2 15 14 2 15 14 19.











ATG GCT AAA TGC TAA TAG CAT


DNA to Proteins


TRY THIS:
What if DNA wanted this sequence to make a protein....
                 TAC TAG CAT GTA ACT

What about this one....
TAC CCT ATA AAA GAT TTA

Gene Therapy?

Editing Your DNA?

Dolly the Sheep

Genetically Modified Foods?




GMO in animals


Final Step in making proteins...

Translation (in the cytoplasm using ribosomes)







With the message from RNA and the transfer RNA available, there has to be something that reads the CODE and "Calls" for the correct tRNA.


PROTEIN SYNTHESIS

Review Game

Activity for Review

Mutations

Thursday, November 5, 2015

Chapter 6

Chapter 6



Section1: Chromosomes & Meiosis





Your body produces 2 types of cells....

1. Germ Cells aka Sex Cells aka Gametes



2. Somatic Cells aka body cells (all other cells in your body)



The number of chromosomes varies within species....

Humans have 23 pairs of chromosomes in each cell (46 chromosomes total)

Fruit flies have 4 pairs of chromosomes in each cell (8 chromosomes total)
Dogs have 39 pairs in each cell
Cats have 19 pairs...


No matter what species you have each chromosome has its pair (the same size and copies of the same genes)

These two pairs of chromosomes are called HOMOLOGOUS CHROMOSOMES



The EXCEPTIONS are the Sex Chromosomes... 

Fertilization happens when an egg (having 23 chromosomes, Haploid cell) combines with the sperm (having 23 chromosomes, Haploid cell) forming a DIPLOID CELL



Haploid Vs Diploid




Syndromes of Sex Linked Chromosomes

Turner Syndrome

                               






Klinefelter Syndrome

Extra Y Chromosome



Some More Info

What about Down Syndrome

 Are Men Going Extinct?



Mitosis vs Meiosis
DIFFERENCES: Meiosis has 2 Divisions & The Result are 2 GENETICALLY DIFFERENT HAPLOID cells
UNIQUE OCCURRENCE IN PROPHASE I
(CROSSOVER)

Review